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KMID : 0383819860330040216
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Tuberculosis and Respiratory Diseases
1986 Volume.33 No. 4 p.216 ~ p.225
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Ventilatory Dynamics in Pulmonary Tuberculosis
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윤덕구(尹德求)/Duk Koo Yun
정태훈(丁泰勳)/박희명(朴熙明)/Tae Hoon Jung/Hi Myung Park
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Abstract
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Ventilatory dynamics was studied in patients with pulmonary tuberculosis by means
of analyses of simultaneously recorded forced expiratory volume (FEV) and maximal
expiratory flow volume (MEFV) curves, and determinations of closing volumes. The
study population consisted of a total of 263 cases comprizing 124 cases of minimal 78
moderatly and 61 far advanced pulmonary tuberculosis.
On the whole, the mean of various volume and flow parameters derived from FEV
and MEFV curves showed progressive decrease as the extent of the disease advanced.
In comparisons of the mean of volume-adjusted flow parameters between patients
groups, all were significantly decreased in far advanced cases than that in the
remainder, whereas significant differences between minimal and moderately advanced
cases were limited to FEV1, Vmax50 and Vmax25. The mean of the
closing volume (CV) and its ratio to VC (CV/VC) tended in far advanced cases was
significantly larger than that in the remainder, with no significant difference between
minimal and moderately advanced cases. This suggests that far advanced pulmonary
tuberculosis is associated with a marked obstruction in large and small airways as well
as restrictive ventilatory impairment. It also suggests that a major difference between
minimal and moderately advanced cases is that the latter has a significant small airway
obstruction compared with the former.
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